Core/Shell structured nanoparticles for imaging and therapy

Applications of gold nanoparticles for medical imaging

Background & Aim: Molecular imaging enables us to non-invasively visualize tissue microstructures and lesion characterization, allowing accurate diagnosis of diseases at early stages. A successful molecular imaging requires a nontoxic contrast agent with high sensitivity. Nowadays, a wide range of nanoparticles have been developed as contrast agents for medical imaging modalities. Here, we revi...

Antibody Targeted Nanoparticles for Imaging and Therapy of Cancer

Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy

Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have s...

Uses of nanoparticles for central nervous system imaging and therapy.

SUMMARY Applications of nanotechnology to medicine are leading to novel means of imaging living systems and of delivering therapy. Much nanotechnology research is focused on methods for imaging central nervous system functions and disease states. In this review, the principles of nanoparticle design and function are discussed with specific emphasis on applications to neuroradiology. In addition...

Multicomponent, Tumor-Homing Chitosan Nanoparticles for Cancer Imaging and Therapy

Current clinical methods for cancer diagnosis and therapy have limitations, although survival periods are increasing as medical technologies develop. In most cancer cases, patient survival is closely related to cancer stage. Late-stage cancer after metastasis is very challenging to cure because current surgical removal of cancer is not precise enough and significantly affects bystander normal t...

Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy

Magnetic iron oxide (IO) nanoparticles with a long blood retention time, biodegradability and low toxicity have emerged as one of the primary nanomaterials for biomedical applications in vitro and in vivo. IO nanoparticles have a large surface area and can be engineered to provide a large number of functional groups for cross-linking to tumor-targeting ligands such as monoclonal antibodies, pep...